Endocrine Abstracts

Object: The aim of the study was to evaluate the safety and efficacy of the pure endoscopic removal of the pituitary adenomas with special references to the complications.Material and methods: The authors analyzed retrospectively a database of 52 consecutive patients (16 males and 36 females) with pituitary adenomas who underwent endoscopic transsphenoidal surgery. Preoperative examination was based on radiological visualization of the tumor and endocrin...

Introduce: Subclinical hyperthyroidism (SH) affects 0.2 - 11.8% of world human population and is associated with important cardiovascular risk factors. It remains controversial whether or not to treat patients with low serum TSH levels. Between unwanted potential outcomes of treatment of SH there is an elevation of the level of serum triglycerides and cholesterol which may be responsible for higher risk of cardiac death.Aim: To estimate an influence of c...

Background: Melatonin as strong antioxidant and free radical scavenger can play important, protective role in disease in which oxidative damage is a significant component e.g.: in coronary heart disease, neoplastic disease, neurodegenerative disease. The aim of our study was determination of the effect of melatonin supplementation on malonyldialdehyde (MDA) concentration and activity of: superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) in patients...

Introduction: Subclinical hyperthyroidism (SH) affects about 1% of world human population at least. The diagnosis of this disease leans on the laboratory criteria only: decreased of TSH and normal FT3 and FT4 concentrations. SH increases mortality mostly due to cardiovascular diseases including overload of the heart and ventricular arrhythmia. These symptoms are anticipated by increasing of left ventricular walls thickness and its mass index.<p class=...

Introduce: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma (DTC) is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. In patients with elevated thyroglobulin levels and with no evidence of disease on radioiodine scintigraphy, scintigraphy with somatostatin analogs can be an alternative imaging modality.The aim: Assessment of scintigraphy with the somatostatin analog 99mTc-HYNIC-TATE to visu...

Introduction: Lack of radioiodine uptake in Differentiated Thyroid Carcinoma is a huge diagnostic and therapeutic problem. This sign is associated with worse prognosis. DOTA-TATE preparation is a somatostatin analogue coupled with 90 Y which emites β (−) radiation. Its use in a treatment depends on excessive expression of somatostatin receptors (SSTR) in malignant tumours.The aim of the study: To present a possibility of treatment o...